Clinical Trial Manager II

About the role

Syneos Health is hiring a Clinical Trial Manager II in Athens, Greece, in a hybrid setting. The role oversees site management, clinical monitoring and central monitoring, with a focus on patient safety, protocol, GCP and regulatory compliance and data integrity. It covers site interactions from post-activation through closeout.

Key responsibilities

• Manage site interactions after activation until closeout, including patient recruitment and investigator payments
• Identify risks to protocol execution and propose mitigations; escalate timeline, quality and budget risks to the project manager
• Take part in key meetings such as the Kick Off Meeting and act as an escalation point for investigators and site staff
• Coordinate with Study Start Up, Patient Recruitment and Data Management to meet site activation, enrollment and database lock targets
• Maintain clinical study tools and templates, including the Clinical Monitoring Plan, and set up CTMS, dashboards and UAT
• Train the study team on protocol, CRFs, dashboards, SOPs and timelines
• Oversee CRAs and Central Monitors, resourcing, site assignments and compliance with the monitoring strategy and risk plans
• Review monitoring documentation (calls, visit reports, correspondence) and document revisions in CTMS
• Support inspection readiness and provide status updates and solutions to the client and leadership

Required profile

• Bachelor's degree or RN in a related field, or equivalent education, training and experience
• Demonstrated ability to lead teams and work in an international environment
• Expertise in site management and monitoring (clinical or central); preferred experience with risk-based monitoring
• Understanding of clinical trial management budgets and financial principles
• Good communication, presentation, conflict resolution and problem-solving skills
• Modest travel, around 20%

Required skills

• Knowledge of Good Clinical Practice (ICH GCP) and other regulatory requirements
• Computer skills
• Familiarity with CTMS, EDC, eDiary, ePROs, TMF, IVRS/IWRS and central monitoring dashboards